Nanogen Nanogaine £35 > Medik8 uk Skin Care products >

Proven Nanogaine with Cu, Mn & SOD More hair growth than with Minoxidil*

Basic explanation of how Nanogaine ingredients work. For results of SOD trials - see below

*Efficacy Data for Superoxide Dismutase (SOD)

Topical application test

The hair of the lumbar region (small 5cm patch) of six C3H mice was cut and 0.1ml of SOD extract was applied twice a day, until hair growth was observed. The area of hair growth was monitored with an image analysing apparatus on days 14, 21 and 28 following the start of the test.

At 1% concentration of SOD, hair growth response was observed in all cases after 14 days and hair growth rate was observed in all areas of treatment. At 0.5% concentration, hair growth response was observed in all cases and hair growth rate was 90%.

In comparison, Minoxidil (2% Rogaine, Upjohn) showed hair growth response for 5 out of the 6 animals in 28 days and hair growth rate was at 57%

In Vitro test

It has been shown that Minoxidil increases the DNA synthesis of skin hair follicle and the synthesis of keratin in the hair follicle (Buhl AE et al., J Invest Dermatol 1991 May; 96(5):73S-74S) so it was decided to use the same test for Superoxide Dismutase for a fair comparison. Addition of only 5-10 microM of SOD extract provoked hair follicle protein synthesis which was 100-200% higher than that of Minoxidil (2%)

We are aware that Minoxidil is usually used at 5% concentration or higher. Nanogaine is formulated with 2% SOD in addition to it's other actives such as Lo-Seb TM and Capilecti

Nanogaine before and after

Nanogaine can be used concurrently with Minoxidil therepy.

A simple search on the Google engine "SOD + Hairloss" will provide multiple references to the other respected sources who have tested SOD for applications in hair loss therapy. Indeed there have been expensive patent fights over this particular ingredient.

Here is a quote from the respected US website Hairlosstalk which we are comfortable quoting as they do NOT stock Nanogaine (we only supply EU)

"SOD's - Also known as Super Oxide Dismutase, these hair loss treatments work by handling the immune response which occurs as a result of excessive DHT in the follicle. When cells sense a foreign body, they release Super Oxide, which typically help defend the body against invading viruses, cells, and foreign tissues. SOD's reduce the presence of this Super Oxide, thus reducing the body's desire to reject the follicle. It's yet another "angle" proven to work in fighting hair loss. SOD's are kind of a hybrid treatment because they also have growth stimulation properties, as well as anti-inflammatory properties."